ANGPTL7 is transcriptionally regulated by SP1 and modulates glucocorticoid-induced cross-linked actin networks in trabecular meshwork cells via the RhoA/ROCK pathway
Abstract Glaucoma is one of the leading causes of worldwide irreversible blindness.Lowering elevated intraocular pressure (IOP) is currently the only effective approach for controlling the progress of glaucoma.Angiopoietin-like 7 (ANGPTL7) takes a key part in elevated outflow resistance of aqueous humor in dysfunctional trabecular meshwork (TM), al